Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.56 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | CPA1 | P15085 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440200 | 0.87 | KMT2A (0.52) | NR4A2RXRARXRBGAAMEN1 | |
| SCHEMBL7440191 | 0.87 | KMT2A (0.52) | NR4A2RXRARXRBGAAMEN1 | |
| Hydrochloric Acid SCHEMBL7896068 | 0.86 | KMT2A (0.51) | NR4A2RXRARXRBGAAMEN1 | |
| Hydrochloric Acid SCHEMBL7896063 | 0.86 | KMT2A (0.51) | NR4A2RXRARXRBGAAMEN1 | |
| SCHEMBL7364281 | 0.83 | REN (0.52) | CTSLMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL5833552 | 0.82 | BCL2 (0.68) | CTSLMMP9MMP8ACEMME | |
| SCHEMBL5833558 | 0.82 | BCL2 (0.68) | CTSLMMP9MMP8ACEMME | |
| SCHEMBL24206195 | 0.81 | MME (0.48) | NR4A2RXRARXRBCTSLRAB9A | |
| SCHEMBL8188148 | 0.81 | MME (0.48) | NR4A2RXRARXRBCTSLRAB9A | |
| SCHEMBL1123299 | 0.81 | GPR132 (0.77) | GPR132GAARAB9AACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323243-B1 | AROMATIC ETHER WITH AMINE OR AMIDE GROUPS | WARNER-LAMBERT COMPANY | 2001-11-27 | — | — | US | disclosed |
| US-6180677-B1 | ANTIEPILEPSY AGENT | WARNER-LAMBERT COMPANY | 2001-01-30 | — | — | US | disclosed |
| WO-2000006535-A1 | TYROSINE-DERIVED COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |