Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | HTR1A | P08908 | 1/20 | 0.72 |
| ▸ | HTR2C | P28335 | 1/20 | 0.72 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.60 |
| ▸ | TUBB | P07437 | 1/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4971210 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL4971223 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL12002057 | 0.90 | JUN (0.63) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL17504467 | 0.90 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL17504469 | 0.90 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL17504465 | 0.90 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL16638706 | 0.89 | HTT (0.72) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL17504463 | 0.87 | JUN (0.75) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL6035433 | 0.87 | JUN (0.75) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL29493678 | 0.87 | TUBB4A (0.59) | KDM4EALDH1A1HPGDHSD17B10HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077964-B1 | FUMAGILLOL DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | CHONG KUN DANG PHARM CORP (KR) | 2002-10-02 | — | — | EP | disclosed |
| EP-1077964-A1 | FUMAGILLOL DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2001-02-28 | — | — | EP | disclosed |
| US-6063812-A | ANGIOGENESIS INHIBITORS, ANTIARTHRITIC AGENTS AND ANTICARCINOGENIC AGENTS PLUS SYNTHESIS | CHONG KUN DANG CORPORATION (KR) | 2000-05-16 | — | — | US | disclosed |
| WO-1999059986-A1 | FUMAGILLOL DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 1999-11-25 | — | — | WO | disclosed |