Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.60 |
| ▸ | TUBB | P07437 | 1/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.60 |
| ▸ | DBH | P09172 | 1/20 | 0.59 |
| ▸ | KRAS | P01116 | 2/20 | 0.57 |
| ▸ | JUN | P05412 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12002057 | 0.90 | JUN (0.63) | HTTGAATUBB4ATUBBTUBA3C | |
| SCHEMBL7450187 | 0.89 | KDM4E (0.72) | HTTGAATUBB4ATUBBTUBA3C | |
| SCHEMBL4971223 | 0.89 | KDM4E (0.72) | HTTGAATUBB4ATUBBTUBA3C | |
| SCHEMBL4971210 | 0.89 | KDM4E (0.72) | HTTGAATUBB4ATUBBTUBA3C | |
| SCHEMBL17529421 | 0.87 | TUBB4A (0.59) | HTTGAATUBB4ATUBBTUBA3C | |
| SCHEMBL29493678 | 0.87 | TUBB4A (0.59) | HTTGAATUBB4ATUBBTUBA3C | |
| SCHEMBL4301544 | 0.85 | GAA (1.00) | HTTGAAKRASALDH1A1KDM4E | |
| SCHEMBL4301538 | 0.85 | GAA (1.00) | HTTGAAKRASALDH1A1KDM4E | |
| SCHEMBL17527242 | 0.83 | TUBB4A (0.78) | HTTGAATUBB4ATUBBTUBA3C | |
| SCHEMBL14175314 | 0.83 | TUBB4A (0.78) | HTTGAATUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006451-B1 | 2-anilinonicotinyl based chalcones useful as potential anticancer agents and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-14 | — | — | US | disclosed |