Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.41 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.40 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512610 | 0.81 | IMPDH2 (0.56) | PLOD2PLOD3PLOD1CTNNB1WNT3A | |
| SCHEMBL6514052 | 0.76 | PLOD2 (0.40) | PLOD2PLOD3PLOD1CTNNB1WNT3A | |
| SCHEMBL9145097 | 0.75 | MAPT (0.56) | PLOD2PLOD3PLOD1CTNNB1WNT3A | |
| SCHEMBL4029594 | 0.70 | HTT (0.58) | PLOD2PLOD3PLOD1MAPTMEN1 | |
| SCHEMBL6169355 | 0.70 | PLOD2 (0.51) | PLOD2PLOD3PLOD1CTNNB1WNT3A | |
| SCHEMBL6166658 | 0.69 | PLOD2 (0.50) | PLOD2PLOD3PLOD1MAPTMEN1 | |
| SCHEMBL709889 | 0.68 | PLOD2 (0.64) | PLOD2PLOD3PLOD1MAPTALDH1A1 | |
| SCHEMBL16930080 | 0.67 | SMPD1 (0.51) | PLOD2MAPTMEN1ALDH1A1GAA | |
| SCHEMBL22805972 | 0.66 | PLOD2 (0.66) | PLOD2PLOD3PLOD1MAPTMEN1 | |
| SCHEMBL6513893 | 0.66 | PLOD2 (0.43) | PLOD2PLOD3PLOD1IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020045654-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | ANDO KAZUO (JP) | 2002-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045654-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | CNR1, PTGER1, PTGS1 | PLOD2 4308/4885PLOD3 3490/4885PLOD1 4213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.