Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.57 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137696 | 0.95 | PLOD2 (0.58) | PLOD2ALDH1A1LMNAALOX15APEX1 | |
| SCHEMBL5042668 | 0.87 | ALDH1A1 (0.58) | PLOD2ALDH1A1LMNAALOX15APEX1 | |
| SCHEMBL1699091 | 0.84 | ALDH1A1 (0.68) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL22805972 | 0.84 | PLOD2 (0.66) | PLOD2ALDH1A1TDP1PLOD3PLOD1 | |
| SCHEMBL4587003 | 0.83 | PLOD2 (0.60) | PLOD2ALDH1A1PLOD3PLOD1NPC1 | |
| SCHEMBL6341239 | 0.83 | ALDH1A1 (0.58) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL153386 | 0.83 | ALDH1A1 (0.76) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL5266206 | 0.82 | PDE4B (0.67) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL22130999 | 0.81 | ALDH1A1 (0.73) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL6483504 | 0.81 | CES2 (0.56) | PLOD2GAAPLOD3PLOD1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917908-B1 | A CONTINUOUS FLOW MICRO-TOTAL PROCESS SYSTEM FOR PREPARATION OF CELECOXIB AND ANALOGS THEREOF | COUNCIL SCIENT IND RES (IN) | 2024-08-14 | — | — | EP | claimed |
| US-11802112-B2 | Continuous flow micro-total process system for preparation of celecoxib and analogs thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-10-31 | — | — | US | claimed |
| US-20220127235-A1 | A CONTINUOUS FLOW MICRO-TOTAL PROCESS SYTEM FOR PREPARATION OF CELCOXIB AND ANALOGS THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-04-28 | — | — | US | claimed |
| EP-3917908-A1 | A CONTINUOUS FLOW MICRO-TOTAL PROCESS SYSTEM FOR PREPARATION OF CELECOXIB AND ANALOGS THEREOF | Council of Scientific & Industrial Research (IN) | 2021-12-08 | — | — | EP | claimed |
| WO-2020157771-A1 | A CONTINUOUS FLOW MICRO-TOTAL PROCESS SYSTEM FOR PREPARATION OF CELECOXIB AND ANALOGS THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-08-06 | — | — | WO | claimed |
| US-4857475-A | Labelled and labellable reagents for fluorometric assays | Ekins, Roger Philip (GB) | 1989-08-15 | — | — | US | claimed |
| US-4565790-A | LANTHANIDE SERIES COMPLEX, B-DIKETONE, DETERGENT | WALLAC OY (FI) | 1986-01-21 | — | — | US | claimed |
| WO-2025002289-A1 | PYRAZOLOHETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 湖南九典制药股份有限公司 | 2025-01-02 | — | — | WO | disclosed |
| EP-3917908-B1 | A CONTINUOUS FLOW MICRO-TOTAL PROCESS SYSTEM FOR PREPARATION OF CELECOXIB AND ANALOGS THEREOF | COUNCIL SCIENT IND RES (IN) | 2024-08-14 | — | — | EP | disclosed |
| CN-118271261-A | Dicarbonyl compound containing cyclobutane segment and synthesis method thereof | 中国科学技术大学 | 2024-07-02 | — | — | CN | disclosed |
| US-11802112-B2 | Continuous flow micro-total process system for preparation of celecoxib and analogs thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-10-31 | — | — | US | disclosed |
| US-20230322684-A1 | COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE | CASE WESTERN RESERVE UNIVERSITY | 2023-10-12 | — | — | US | disclosed |
| US-20230322684-A1 | COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE | CASE WESTERN RESERVE UNIVERSITY | 2023-10-12 | — | — | US | disclosed |
| US-6403629-B2 | 1-(P-(METHYLSULFONAMIDO)PHENYL)-3-TRIFLUOROMETHYL-5-PHENYLPYRA ZOLONE AND DERIVATIVES; ANTIINFLAMMATORY AGENTS | J.B. CHEMICAL AND PHARMACEUTICALS LIMITED (IN) | 2002-06-11 | — | — | US | disclosed |
| US-20010055776-A1 | High throughput cell-based assay kits | GREENWALT DALE (US) | 2001-12-27 | — | — | US | disclosed |
| US-20010047023-A1 | New Heterocyclic compounds for therapeutic use | J.B. CHEMICALS & PHARMACEUTICALS LIMITED | 2001-11-29 | — | — | US | disclosed |
| WO-2001040216-A1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PRODUCTS INC. (US) | 2001-06-07 | — | — | WO | disclosed |
| US-4556621-A | Electrophotographic recording material containing a metal-1,3-diketone complex | BASF AKTIENGESELLSCHAFT (DE) | 1985-12-03 | — | — | US | disclosed |
| EP-0133469-A1 | Electrophotographic recording materials with improved photosensitivity | BASF Aktiengesellschaft (DE) | 1985-02-27 | — | — | EP | disclosed |
| US-4176918-A | Fluorescent liquid crystal display | TEMPLE UNIVERSITY (US) | 1979-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11802112-B2 | Continuous flow micro-total process system for preparation of celecoxib and analogs thereof | PTGES2, PTGS2, CYP2J2 | PLOD2 3454/4885ALDH1A1 2787/4885LMNA 4602/4885 |
| US-20010047023-A1 | New Heterocyclic compounds for therapeutic use | AADAC, NAT1, FPR1 | PLOD2 2358/4885ALDH1A1 1510/4885LMNA 3310/4885 |
| US-20230322684-A1 | COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE | HPGD, GCDH, HPGDS | PLOD2 340/4885ALDH1A1 136/4885LMNA 1538/4885 |
| US-20220127235-A1 | A CONTINUOUS FLOW MICRO-TOTAL PROCESS SYTEM FOR PREPARATION OF CELCOXIB AND ANALOGS THEREOF | PTGES2, PTGS2, P2RX2 | PLOD2 2433/4885ALDH1A1 4668/4885LMNA 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.