Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 9/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ITGAV | P06756 | 4/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.45 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367276 | 0.88 | ITGB1 (0.48) | ITGB1ITGA5MEN1KMT2AITGAV | |
| SCHEMBL6373924 | 0.84 | ITGB1 (0.59) | ITGB1ITGA5ITGAVITGA4ITGA2 | |
| SCHEMBL6374041 | 0.83 | MMP8 (0.60) | ITGB1ITGA5ITGAVITGA4ITGB7 | |
| SCHEMBL6368881 | 0.81 | MEN1 (0.49) | MEN1KMT2AATMHCRTR1HCRTR2 | |
| SCHEMBL6368648 | 0.79 | ITGB1 (0.50) | ITGB1ITGA5ITGAVITGA4ITGA2 | |
| SCHEMBL6368978 | 0.78 | ITGB1 (0.52) | ITGB1ITGA5ITGAVITGA4ITGA2 | |
| SCHEMBL6373884 | 0.76 | ITGB1 (0.45) | ITGB1ITGA5ITGAVITGA4ITGB7 | |
| SCHEMBL6368195 | 0.76 | ITGB1 (0.64) | ITGB1ITGA5ITGAVITGA4ITGA2 | |
| SCHEMBL6429204 | 0.75 | ITGB1 (0.62) | ITGB1ITGA5ITGAVITGA4ITGA2 | |
| SCHEMBL7067011 | 0.75 | ITGB1 (0.59) | ITGB1ITGA5ITGA4ITGA2ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999064395-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1999-12-16 | — | — | WO | claimed |