Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | CDK4 | P11802 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 6/20 | 0.53 |
| ▸ | ACHE | P22303 | 6/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064581 | 0.80 | KMT2A (1.00) | KMT2ANPC1RAB9ACDK4MEN1 | |
| SCHEMBL31379599 | 0.80 | AOC3 (0.51) | KMT2ABCHEACHECHRM2CHRM1 | |
| SCHEMBL17886232 | 0.80 | AOC3 (0.51) | KMT2ABCHEACHECHRM2CHRM1 | |
| SCHEMBL7442885 | 0.79 | KMT2A (0.77) | KMT2ANPC1RAB9ABCHEACHE | |
| SCHEMBL15892683 | 0.78 | KMT2A (0.67) | KMT2ANPC1RAB9ABCHEACHE | |
| SCHEMBL23925502 | 0.78 | AOC3 (0.61) | KMT2ACDK4BCHEACHECHRM2 | |
| SCHEMBL362209 | 0.77 | LMNA (0.59) | SMN1; SMN2 | |
| SCHEMBL29590071 | 0.77 | LMNA (0.59) | SMN1; SMN2 | |
| SCHEMBL12289378 | 0.76 | RAB9A (0.74) | KMT2ANPC1RAB9ACDK4MEN1 | |
| Hydrochloric Acid SCHEMBL7413528 | 0.76 | LMNA (0.57) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | claimed |
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | claimed |