Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.46 |
| ▸ | F2R | P25116 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501427 | 0.91 | ITGB3 (0.51) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7816444 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7450393 | 0.85 | ITGB3 (0.44) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7502057 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7450396 | 0.84 | MEN1 (0.43) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7501010 | 0.84 | ITGB3 (0.48) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7506668 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7445610 | 0.83 | ALDH1A1 (0.39) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7498442 | 0.82 | ITGB3 (0.50) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7441420 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BF2RMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |