SCHEMBL7450492

SCHEMBL7450492

CC(C)(C)[Si](C)(C)OC(CCO)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7450483 1.00
SCHEMBL31293454 0.79 GABRP (0.33)
SCHEMBL7803770 0.76 CETP (0.30)
SCHEMBL15653296 0.75
SCHEMBL25230017 0.74
SCHEMBL25230019 0.74
SCHEMBL8433680 0.74 PGD (0.31)
SCHEMBL29533691 0.74 PGD (0.31)
SCHEMBL8433687 0.74 PGD (0.31)
SCHEMBL22123648 0.74 L3MBTL1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034094-A1 COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS KOJIN THERAPEUTICS INC (US) 2026-02-05 US disclosed
EP-4565228-A2 COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS Kojin Therapeutics, Inc. (US) 2025-06-11 EP disclosed
WO-2024030960-A2 COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS Kojin Therapeutics, Inc. (US) 2024-02-08 WO disclosed
WO-2023085367-A1 GCL INHIBITOR 小野薬品工業株式会社 2023-05-19 WO disclosed
US-5969146-A MONOAMINE OXIDASE INHIBITORS SYNTHELABO (FR) 1999-10-19 US disclosed
EP-0891358-A1 OXAZOLIDIN-2-ONE DERIVATIVES, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF SYNTHELABO (FR) 1999-01-20 EP disclosed
WO-1997013768-A1 OXAZOLIDIN-2-ONE DERIVATIVES, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF SYNTHELABO (FR) 1997-04-17 WO disclosed