Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451494 | 0.82 | APEX1 (0.47) | KMT2ALMNAMAPK1 | |
| SCHEMBL7450532 | 0.81 | PDE5A (0.48) | KMT2A | |
| SCHEMBL7922235 | 0.80 | CREBBP (0.38) | RXFP1KMT2APARP1HPGDALOX15 | |
| SCHEMBL7450580 | 0.79 | LMNA (0.41) | HSD17B10PTPN2PTPN1KMT2ALMNA | |
| SCHEMBL8125815 | 0.76 | TERT (0.62) | HSD17B10RXFP1KMT2ALMNAMAPK1 | |
| SCHEMBL7362179 | 0.75 | KMT2A (0.45) | KMT2AALOX15LMNAMAPK1RAB9A | |
| SCHEMBL963 | 0.73 | MAPT (0.48) | HSD17B10RXFP1KMT2APARP1ALOX15 | |
| SCHEMBL3133104 | 0.73 | CA2 (0.35) | HSD17B10RXFP1KMT2ALMNAMAPK1 | |
| SCHEMBL6806762 | 0.70 | RXFP1 (0.38) | HSD17B10RXFP1MRGPRX1LMNAMAPK1 | |
| SCHEMBL1705329 | 0.70 | TERT (0.61) | RXFP1LMNARAB9AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087888-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | SK CHEMICALS CO., LTD. (KR) | 2001-11-22 | — | — | WO | disclosed |