Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369750 | 0.96 | VCAM1 (0.44) | GPR35EGFRVCAM1TPMTGRM6 | |
| SCHEMBL8728250 | 0.87 | GPR35 (0.53) | GPR35VCAM1GRM6GRIA1GRIA2 | |
| SCHEMBL7373383 | 0.81 | TPMT (0.44) | GPR35EGFRVCAM1TPMTGRM6 | |
| SCHEMBL7371372 | 0.72 | KDM4E (0.49) | GPR35TPMT | |
| SCHEMBL2958280 | 0.72 | VCAM1 (0.51) | GPR35VCAM1GRM6GRIA1GRIA2 | |
| SCHEMBL6815361 | 0.71 | GPR35 (0.56) | GPR35EGFRTPMT | |
| SCHEMBL5653715 | 0.71 | GPR35 (0.51) | GPR35EGFRTPMT | |
| SCHEMBL7369437 | 0.70 | VCAM1 (0.45) | GPR35VCAM1GRM6GRIA1GRIA2 | |
| SCHEMBL9736340 | 0.70 | VCAM1 (0.49) | GPR35VCAM1TPMTGRM6GRIA1 | |
| SCHEMBL16901738 | 0.70 | GPR35 (0.44) | GPR35VCAM1TPMTGRM6GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237929-B1 | 3,5-DISUBSTITUTED PYROCATECHOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |