Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11871822 | 0.90 | VCAM1 (0.55) | VCAM1XDHGRIA1GRIA2GRIA3 | |
| SCHEMBL20589392 | 0.84 | VCAM1 (0.49) | VCAM1XDHGPR35ALDH1A1LMNA | |
| SCHEMBL25514817 | 0.84 | VCAM1 (0.49) | VCAM1XDHGPR35ALDH1A1LMNA | |
| SCHEMBL16901738 | 0.84 | GPR35 (0.44) | VCAM1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL30673260 | 0.83 | GPR35 (0.48) | VCAM1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL26927308 | 0.83 | GPR35 (0.48) | VCAM1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL225343 | 0.82 | ALDH1A1 (0.50) | GPR35TPMTALDH1A1LMNAMAPT | |
| SCHEMBL4054047 | 0.80 | TDP1 (0.44) | VCAM1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11730155 | 0.79 | PKM (0.47) | VCAM1XDHGPR35TPMTALDH1A1 | |
| SCHEMBL11748972 | 0.79 | ALDH1A1 (0.47) | GRIA1GRIA2GRIA3GRIA4GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086128-A | HIGH MOLECULAR WEIGHT ARYLENE SULPHIDE POLYMER MELT MIXED WITH AROMATIC NITRO COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| EP-0345550-A2 | High molecular weight arylene sulphide polymers | BAYER AG (DE) | 1989-12-13 | — | — | EP | disclosed |
| US-3935183-A | WATER INSOLUBLE DYE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) | 1976-01-27 | — | — | US | disclosed |