Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 3/20 | 0.41 |
| ▸ | NOS2 | P35228 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8813141 | 0.87 | NAPRT (0.44) | NAPRTNOS3NOS2NOS1KMT2A | |
| SCHEMBL7553608 | 0.87 | NAPRT (0.46) | NAPRTNOS3NOS2NOS1KMT2A | |
| SCHEMBL1260539 | 0.80 | NOS2 (0.52) | NAPRTNOS3NOS2NOS1KMT2A | |
| SCHEMBL7548361 | 0.79 | NAPRT (0.53) | NAPRTNOS3NOS2NOS1KMT2A | |
| SCHEMBL7547161 | 0.79 | NAPRT (0.42) | NAPRTNOS3NOS2KMT2ACYP3A4 | |
| SCHEMBL7551656 | 0.78 | TDP1 (0.39) | NAPRTNOS3NOS2KMT2AL3MBTL1 | |
| SCHEMBL7547531 | 0.78 | NAPRT (0.44) | NAPRTNOS3NOS2NOS1KMT2A | |
| SCHEMBL19857454 | 0.78 | NAPRT (0.57) | NAPRTKMT2AL3MBTL1TDP1CYP3A4 | |
| SCHEMBL8798672 | 0.77 | RAB9A (0.42) | NAPRTKMT2AL3MBTL1KDM4EKDM4C | |
| SCHEMBL20520335 | 0.77 | NAPRT (0.47) | NAPRTNOS3NOS2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |