Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876215 | 0.83 | PAX8 (0.47) | LMNASMN1; SMN2PAX8CTSLHTT | |
| SCHEMBL7645777 | 0.80 | SMN1; SMN2 (0.50) | RAB9ANPC1LMNASMN1; SMN2MEN1 | |
| SCHEMBL6182408 | 0.79 | GAA (0.46) | LMNATSHRKMT2AHTT | |
| SCHEMBL5521758 | 0.78 | PRMT5 (0.48) | PAX8CTSLCTSBCTSS | |
| SCHEMBL6183852 | 0.78 | CTSL (0.61) | CTSLCTSBCTSS | |
| SCHEMBL7551492 | 0.76 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2KMT2ACTSLCTSB | |
| SCHEMBL6185799 | 0.75 | PLK1 (0.50) | RAB9ANPC1LMNASMN1; SMN2HTT | |
| SCHEMBL6182813 | 0.75 | MAP3K5 (0.43) | CTSLCTSBCTSSHTT | |
| SCHEMBL6203504 | 0.74 | LOXL2 (0.42) | RAB9ANPC1KMT2ACTSLCTSB | |
| SCHEMBL7449982 | 0.74 | POLB (0.47) | RAB9ANPC1LMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002539192-A | — | — | 2002-11-19 | — | — | JP | claimed |
| EP-1161415-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | claimed |
| WO-2000055126-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | claimed |