Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 2/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451867 | 1.00 | SYK (0.32) | SYKCTSDBACE1KLK7KLK5 | |
| SCHEMBL7558417 | 1.00 | SYK (0.32) | SYKCTSDBACE1KLK7KLK5 | |
| SCHEMBL7552350 | 1.00 | SYK (0.32) | SYKCTSDBACE1KLK7KLK5 | |
| SCHEMBL7447808 | 0.86 | — | — | |
| SCHEMBL7526880 | 0.82 | CTSD (0.32) | CTSDBACE1KLK7KLK5GAA | |
| SCHEMBL7526876 | 0.82 | CTSD (0.32) | CTSDBACE1KLK7KLK5GAA | |
| SCHEMBL7513722 | 0.82 | CTSD (0.32) | CTSDBACE1KLK7KLK5GAA | |
| SCHEMBL7513728 | 0.82 | CTSD (0.32) | CTSDBACE1KLK7KLK5GAA | |
| SCHEMBL7513733 | 0.80 | CTSK (0.45) | CTSDBACE1KLK7KLK5CTSS | |
| SCHEMBL15045018 | 0.66 | NFKB1 (0.44) | GAACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153022-A4 | PROTHEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1153022-A1 | PROTHEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000049011-A1 | PROTHEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-08-24 | — | — | WO | disclosed |