Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 10/20 | 0.76 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | F2R | P25116 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8278751 | 0.91 | MTNR1B (0.89) | MTNR1BMTNR1ARAB9AALDH1A1HPGD | |
| SCHEMBL8644515 | 0.89 | MTNR1B (0.68) | MTNR1BMTNR1ARAB9AALDH1A1HPGD | |
| SCHEMBL8645993 | 0.84 | CYP2C19 (0.68) | MTNR1BMTNR1ARAB9AALDH1A1HPGD | |
| SCHEMBL12383061 | 0.84 | F2R (0.77) | ALDH1A1HPGDGAAF2RPOLB | |
| SCHEMBL13753200 | 0.83 | MTNR1B (0.75) | MTNR1BMTNR1ARAB9AALDH1A1HPGD | |
| SCHEMBL30605275 | 0.82 | MTNR1B (0.73) | MTNR1BMTNR1ARAB9AALDH1A1HPGD | |
| SCHEMBL25938755 | 0.82 | MTNR1B (0.73) | MTNR1BMTNR1ARAB9AALDH1A1HPGD | |
| SCHEMBL4611370 | 0.81 | MTNR1B (0.72) | MTNR1BMTNR1ARAB9AALDH1A1HPGD | |
| SCHEMBL8142313 | 0.81 | CYP3A4 (0.59) | MTNR1BMTNR1ARAB9AALDH1A1HPGD | |
| SCHEMBL10975643 | 0.80 | F2R (0.73) | MTNR1BRAB9AALDH1A1HPGDF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910356-A4 | BIPHENYLAMIDO DERIVATIVES AS MELATONERGIC AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2002-02-13 | — | — | EP | claimed |
| EP-0910356-A1 | BIPHENYLAMIDO DERIVATIVES AS MELATONERGIC AGENTS | Bristol-Myers Squibb Company (US) | 1999-04-28 | — | — | EP | claimed |
| US-5808151-A | CONTROLLING SLEEP | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| WO-1997038682-A1 | BIPHENYLAMIDO DERIVATIVES AS MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-10-23 | — | — | WO | claimed |
| US-5808151-A | CONTROLLING SLEEP | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-09-15 | — | — | US | disclosed |