Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CDK8 | P49336 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2502606 | 0.91 | NPC1 (0.76) | MTNR1AMTNR1BNPC1HPGDALDH1A1 | |
| SCHEMBL8644515 | 0.87 | MTNR1B (0.68) | CYP2C19MTNR1AMTNR1BNPC1HPGD | |
| SCHEMBL7452038 | 0.84 | MTNR1B (0.76) | MTNR1AMTNR1BHPGDALDH1A1CNR1 | |
| SCHEMBL9495103 | 0.83 | SMN1; SMN2 (0.71) | CYP2C19MTNR1AMTNR1BNPC1HPGD | |
| SCHEMBL8228787 | 0.82 | CYP2C19 (0.67) | CYP2C19MTNR1AMTNR1BNPC1HPGD | |
| SCHEMBL8642110 | 0.81 | CNR1 (0.64) | NPC1ALDH1A1SMN1; SMN2TP53CNR1 | |
| SCHEMBL7284435 | 0.80 | HPGD (0.77) | MTNR1AMTNR1BNPC1HPGDALDH1A1 | |
| SCHEMBL5142657 | 0.80 | NPC1 (0.75) | MTNR1AMTNR1BNPC1HPGDALDH1A1 | |
| SCHEMBL8365621 | 0.79 | CYP2C19 (0.59) | CYP2C19MTNR1AMTNR1BHPGDALDH1A1 | |
| SCHEMBL8144502 | 0.79 | MTNR1B (1.00) | MTNR1AMTNR1BNPC1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808151-A | CONTROLLING SLEEP | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-09-15 | — | — | US | disclosed |