Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | TYMS | P04818 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.69 |
| ▸ | DHFR | P00374 | 10/20 | 0.64 |
| ▸ | TLR4 | O00206 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminopterin SCHEMBL1527810 | 0.99 | KDM4E (0.68) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Aminopterin SCHEMBL5487391 | 0.92 | KDM4E (0.61) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Aminopterin SCHEMBL74532 | 0.91 | DHFR (0.61) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Aminopterin SCHEMBL29443569 | 0.91 | DHFR (0.76) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Aminopterin SCHEMBL20769794 | 0.91 | DHFR (0.76) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Aminopterin SCHEMBL29398079 | 0.91 | DHFR (0.76) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Aminopterin SCHEMBL8161477 | 0.91 | DHFR (0.76) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Aminopterin SCHEMBL9514067 | 0.91 | DHFR (0.76) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Aminopterin SCHEMBL1626034 | 0.91 | DHFR (0.76) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Aminopterin SCHEMBL8887 | 0.91 | DHFR (0.76) | KDM4EMEN1ALDH1A1TYMSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3282014-B1 | CANCER CELL-SPECIFIC ANTI-PODOCALYXIN ANTIBODY AND METHOD FOR PRODUCING SAME | UNIV TOHOKU (JP) | 2023-09-06 | — | — | EP | disclosed |
| US-11066482-B2 | Specific plasmin inactivation by anticatalytic antibody | REED GUY L (US) | 2021-07-20 | — | — | US | disclosed |
| US-10906972-B2 | Cancer cell specific anti-podocalyxin antibody and method for producing same | TOHOKU UNIVERSITY (JP) | 2021-02-02 | — | — | US | disclosed |
| US-10696743-B2 | Diagnosis and treatment of cancer using anti-desmoglein-3 antibodies | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-06-30 | — | — | US | disclosed |
| EP-3459974-A1 | SPECIFIC PLASMIN INACTIVATION BY ANTICATALYTIC ANTIBODY | Reed, Guy L. (US) | 2019-03-27 | — | — | EP | disclosed |
| US-20190085097-A1 | Specific Plasmin Inactivation by Anticatalytic Antibody | REED GUY L (US) | 2019-03-21 | — | — | US | disclosed |
| US-20190024114-A1 | METHOD OF PRODUCING A PRODUCTION CELL LINE | BAUER, ANTON (AT) | 2019-01-24 | — | — | US | disclosed |
| EP-3111955-B1 | DIAGNOSIS AND TREATMENT OF CANCER USING ANTI-DESMOGLEIN-3 ANTIBODY | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2019-01-23 | — | — | EP | disclosed |
| EP-3402886-A1 | METHOD OF PRODUCING A PRODUCTION CELL LINE | Bauer, Anton (AT) | 2018-11-21 | — | — | EP | disclosed |
| US-20180134786-A1 | Cancer Cell Specific Anti-Podocalyxin Antibody and Method for Producing Same | ZENOGEN PHARMA CO., LTD. (JP) | 2018-05-17 | — | — | US | disclosed |
| WO-1993002190-A1 | PRODUCTION OF ANTIBODIES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-02-04 | — | — | WO | disclosed |
| EP-0523949-A1 | Production of antibodies | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-01-20 | — | — | EP | disclosed |
| US-5110738-A | Genetic engineering; hybridomas of melanoma and spleen cells | RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0236637-B1 | MONOCLONAL ANTIBODY CAPABLE OF RECOGNIZING ARTERIOSCLEROTIC LESIONS AND AGENTS FOR DETECTING AND TREATING ARTERIOSCLEROSIS | Research Development Corporation of Japan (JP) | 1991-07-03 | — | — | EP | disclosed |
| EP-0236637-A1 | Monoclonal antibody capable of recognizing arteriosclerotic lesions and agents for detecting and treating arteriosclerosis | Research Development Corporation of Japan (JP) | 1987-09-16 | — | — | EP | disclosed |
| EP-0090898-B1 | CELL-DRIVEN VIRAL TRANSFER IN EUKARYOTES | GENETIC SYSTEMS CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |
| EP-0189688-A2 | Monoclonal antibody capable of recognizing arteriosclerotic lesions and agents for detecting and treating arteriosclerosis | Research Development Corporation of Japan (JP) | 1986-08-06 | — | — | EP | disclosed |
| US-4464465-A | Cell-driven viral transfer in eukaryotes | GENETIC SYSTEMS CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |
| EP-0090898-A2 | Cell-driven viral transfer in Eukaryotes | GENETIC SYSTEMS CORPORATION (US) | 1983-10-12 | — | — | EP | disclosed |
| EP-0077571-A2 | Process for producing a lymphokine | AJINOMOTO CO., INC. (JP) | 1983-04-27 | — | — | EP | disclosed |