Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456516 | 0.95 | MAPKAPK2 (0.30) | MAPKAPK2 | |
| SCHEMBL7459869 | 0.88 | MAPT (0.36) | KCNH2 | |
| SCHEMBL7463506 | 0.83 | MAPKAPK2 (0.31) | MAPKAPK2 | |
| SCHEMBL7460783 | 0.83 | MAPKAPK2 (0.35) | MAPKAPK2KCNH2 | |
| SCHEMBL7463531 | 0.81 | MAPKAPK2 (0.34) | MAPKAPK2KCNH2 | |
| SCHEMBL963990 | 0.81 | SIRT2 (0.40) | MAPKAPK2KCNH2 | |
| SCHEMBL7456651 | 0.80 | ALDH1A1 (0.34) | MAPKAPK2KCNH2 | |
| SCHEMBL7463111 | 0.80 | ALDH1A1 (0.34) | MAPKAPK2KCNH2 | |
| SCHEMBL965656 | 0.80 | SIRT2 (0.37) | MAPKAPK2KCNH2 | |
| SCHEMBL7459313 | 0.79 | NOTUM (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498179-B1 | SUCH AS 4-(4-CHLOROPHENYL)-5-(3-(2-METHOXYPHENOXY)PROPYL)-2-(2-METHYL-1 -IMIDAZOLYL)OXAZOLE; INSULIN SECERTION PROMOTING AND BLOOD SUGAR DEPRESSING EFFECT; DIABETES; LOW TOXICITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-12-24 | — | — | US | disclosed |
| EP-0891340-B1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-11-13 | — | — | EP | disclosed |
| US-6177452-B1 | ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-23 | — | — | US | disclosed |