Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.33 |
| ▸ | RXRG | P48443 | 3/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460783 | 0.85 | MAPKAPK2 (0.35) | ALDH1A1RXRARXRBRXRGMAPKAPK2 | |
| SCHEMBL6606347 | 0.84 | RXRA (0.47) | ALDH1A1RXRARXRBRXRGSMN1; SMN2 | |
| SCHEMBL963990 | 0.83 | SIRT2 (0.40) | ALDH1A1RXRARXRBRXRGMAPKAPK2 | |
| SCHEMBL7463531 | 0.83 | MAPKAPK2 (0.34) | ALDH1A1MAPKAPK2PSEN1PSEN2APH1B | |
| SCHEMBL7462674 | 0.83 | NR4A2 (0.37) | RXRARXRBRXRGMAPKAPK2CYP3A4 | |
| SCHEMBL965656 | 0.83 | SIRT2 (0.37) | ALDH1A1RXRARXRBRXRGMAPKAPK2 | |
| SCHEMBL7456651 | 0.83 | ALDH1A1 (0.34) | ALDH1A1MAPKAPK2CYP3A4CYP2D6KCNH2 | |
| SCHEMBL7461461 | 0.82 | RXRA (0.43) | RXRARXRBRXRG | |
| SCHEMBL1360344 | 0.82 | SIRT2 (0.36) | RXRARXRBRXRGMAPKAPK2CYP3A4 | |
| SCHEMBL964061 | 0.82 | SIRT2 (0.36) | RXRARXRBRXRGMAPKAPK2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891340-B1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-11-13 | — | — | EP | disclosed |