Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094085 | 0.82 | CCR6 (0.43) | L3MBTL1TDP1MAPK1ALDH1A1LMNA | |
| SCHEMBL6893551 | 0.71 | TSHR (0.47) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL3650581 | 0.71 | ALDH1A1 (0.43) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL11430998 | 0.68 | TSHR (0.50) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL4920502 | 0.67 | NPC1 (0.48) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL11546490 | 0.66 | TSHR (0.50) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL2870267 | 0.65 | CHRNB2 (0.47) | TSHRL3MBTL1TDP1MAPK1ALDH1A1 | |
| SCHEMBL4919040 | 0.65 | TSHR (0.46) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL27983244 | 0.65 | NPC1 (0.59) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL4921591 | 0.65 | TSHR (0.49) | TSHRL3MBTL1TDP1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025090-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2000-11-08 | — | — | EP | disclosed |
| EP-1025090-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999015508-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-01 | — | — | WO | disclosed |