Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459569 | 0.89 | ALDH1A1 (0.32) | P2RX7L3MBTL1ALDH1A1NR3C2LMNA | |
| SCHEMBL7459534 | 0.85 | BRS3 (0.37) | — | |
| SCHEMBL9214487 | 0.84 | ALDH1A1 (0.34) | P2RX7PKMHTTALDH1A1KMT2A | |
| SCHEMBL9259502 | 0.84 | USP30 (0.35) | L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9275361 | 0.82 | ALDH1A1 (0.39) | HTTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9218390 | 0.79 | GAA (0.47) | ALDH1A1KMT2AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7459545 | 0.79 | — | — | |
| SCHEMBL7458077 | 0.73 | ALDH1A1 (0.34) | P2RX7L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9216139 | 0.72 | ALDH1A1 (0.32) | P2RX7HTTALDH1A1KMT2ALMNA | |
| SCHEMBL7455828 | 0.69 | GAA (0.49) | ALDH1A1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639190-B1 | PYRIDINE SULFONYL UREA DERIVATIVES | LG CHEM INVESTMENT LTD (KR) | 2002-01-09 | — | — | EP | disclosed |