Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216139 | 0.87 | ALDH1A1 (0.32) | ALDH1A1HTTP2RX7CHRNA7CA12 | |
| SCHEMBL7454464 | 0.84 | P2RX7 (0.32) | ALDH1A1HTTP2RX7KMT2AKDM4E | |
| SCHEMBL9259502 | 0.82 | USP30 (0.35) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL7459545 | 0.82 | — | — | |
| SCHEMBL9275361 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HTTKMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL7459534 | 0.79 | BRS3 (0.37) | — | |
| SCHEMBL9207637 | 0.76 | FTO (0.36) | CHRNA7CA12CA1CA2CA9 | |
| SCHEMBL9214491 | 0.74 | ALDH1A1 (0.34) | ALDH1A1HTTP2RX7CA12CA1 | |
| SCHEMBL9218390 | 0.73 | GAA (0.47) | ALDH1A1KMT2AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7459569 | 0.72 | ALDH1A1 (0.32) | ALDH1A1P2RX7LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5461026-A | Pyridine sulfonyl urea derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-10-24 | — | — | US | disclosed |
| EP-0639190-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992014728-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-09-03 | — | — | WO | disclosed |