Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454464 | 0.89 | P2RX7 (0.32) | ALDH1A1P2RX7L3MBTL1NR3C2LMNA | |
| SCHEMBL9216139 | 0.84 | ALDH1A1 (0.32) | ALDH1A1P2RX7LMNAMAPK1 | |
| SCHEMBL7458077 | 0.82 | ALDH1A1 (0.34) | ALDH1A1P2RX7L3MBTL1LMNAMAPK1 | |
| SCHEMBL7455828 | 0.79 | GAA (0.49) | ALDH1A1 | |
| SCHEMBL7459534 | 0.74 | BRS3 (0.37) | — | |
| SCHEMBL7455841 | 0.73 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL9259502 | 0.73 | USP30 (0.35) | ALDH1A1L3MBTL1 | |
| SCHEMBL7464310 | 0.73 | — | — | |
| SCHEMBL9214487 | 0.72 | ALDH1A1 (0.34) | ALDH1A1P2RX7LMNAMAPK1 | |
| SCHEMBL9275361 | 0.71 | ALDH1A1 (0.39) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639190-B1 | PYRIDINE SULFONYL UREA DERIVATIVES | LG CHEM INVESTMENT LTD (KR) | 2002-01-09 | — | — | EP | disclosed |