Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PLAT | P00750 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 2/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 11/20 | 0.39 |
| ▸ | FEN1 | P39748 | 11/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368049 | 0.85 | F2 (0.59) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7459605 | 0.85 | F2 (0.59) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7454504 | 0.82 | ALOX5AP (0.38) | ALOX5APFEN1 | |
| SCHEMBL7365001 | 0.76 | ALOX5AP (0.42) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7690246 | 0.75 | F2 (0.41) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7451721 | 0.75 | F2 (0.41) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7057459 | 0.74 | RORC (0.44) | F10ALOX5APFEN1 | |
| SCHEMBL7358633 | 0.73 | ALOX5AP (0.43) | F2PRSS1PRSS2PRSS3ALOX5AP | |
| SCHEMBL5885954 | 0.71 | NR3C1 (0.41) | ALOX5APFEN1 | |
| SCHEMBL7450967 | 0.71 | F2 (0.81) | F2PRSS1PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |