Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.68 |
| ▸ | SMARCA2 | P51531 | 7/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459153 | 0.89 | GRM5 (0.72) | GRM5SMARCA2SMARCA4MAPTCSNK1E | |
| SCHEMBL7453851 | 0.89 | GRM5 (0.69) | GRM5SMARCA2SMARCA4NPC1RAB9A | |
| SCHEMBL7449344 | 0.89 | GRM5 (0.54) | GRM5SMARCA2SMARCA4NPC1RAB9A | |
| SCHEMBL7458646 | 0.87 | GRM5 (0.73) | GRM5SMARCA2SMARCA4NPC1RAB9A | |
| SCHEMBL12067825 | 0.86 | GRM5 (0.52) | GRM5NPC1RAB9ALMNATP53 | |
| SCHEMBL7454043 | 0.85 | GRM5 (0.71) | GRM5SMARCA2SMARCA4NPC1RAB9A | |
| SCHEMBL7445410 | 0.81 | GRM5 (1.00) | GRM5SMARCA2SMARCA4NPC1RAB9A | |
| SCHEMBL7458429 | 0.80 | GRM5 (0.61) | GRM5SMARCA2SMARCA4MAPTGRM4 | |
| SCHEMBL7453711 | 0.80 | GRM5 (0.58) | GRM5SMARCA2SMARCA4NPC1RAB9A | |
| SCHEMBL7451341 | 0.80 | GRM5 (0.53) | GRM5SMARCA2SMARCA4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151361-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151361-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |