Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11462791 | 0.95 | CCR2 (0.49) | CCR2 | |
| SCHEMBL6541445 | 0.87 | CXCR4 (0.55) | OPRD1CCR2 | |
| SCHEMBL6541449 | 0.87 | CXCR4 (0.55) | OPRD1CCR2 | |
| SCHEMBL24447814 | 0.83 | MAPK1 (0.59) | OPRD1 | |
| SCHEMBL11990423 | 0.83 | MAPK1 (0.59) | OPRD1 | |
| SCHEMBL7552049 | 0.82 | CXCR4 (0.56) | CCR2 | |
| SCHEMBL13354467 | 0.82 | OPRD1 (0.52) | OPRD1 | |
| SCHEMBL5967967 | 0.81 | OPRD1 (0.53) | OPRD1 | |
| SCHEMBL27492 | 0.81 | — | — | |
| SCHEMBL14454201 | 0.81 | CCR2 (0.48) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137412-A4 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | AMERICAN BIOGENETIC SCIENCES (US) | 2002-04-03 | — | — | EP | claimed |
| EP-1137412-A2 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-10-04 | — | — | EP | claimed |
| WO-2000033788-A2 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | AMERICAN BIOGENETIC SCIENCES INC. (US) | 2000-06-15 | — | — | WO | claimed |
| EP-1137412-A4 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | AMERICAN BIOGENETIC SCIENCES (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1137412-A2 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000033788-A2 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | AMERICAN BIOGENETIC SCIENCES INC. (US) | 2000-06-15 | — | — | WO | disclosed |