Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CCR5 | P51681 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470084 | 0.95 | OPRM1 (0.53) | OPRM1KDM4ELMNAGAACCR5 | |
| SCHEMBL7465426 | 0.91 | SLC6A2 (0.49) | OPRM1KDM4ELMNAGAACCR5 | |
| SCHEMBL7465552 | 0.89 | NPSR1 (0.49) | OPRM1KDM4ELMNAGAACCR5 | |
| Hydrochloric Acid SCHEMBL7465772 | 0.87 | CCR5 (0.70) | OPRM1CCR5 | |
| SCHEMBL7517595 | 0.85 | CCR5 (0.51) | OPRM1CCR5CCR3SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL7463538 | 0.83 | CCR5 (0.56) | OPRM1KDM4ECCR5 | |
| Hydrochloric Acid SCHEMBL7453187 | 0.83 | CCR5 (0.63) | OPRM1CCR5 | |
| Hydrochloric Acid SCHEMBL7470211 | 0.83 | CCR5 (0.63) | OPRM1CCR5 | |
| Hydrochloric Acid SCHEMBL7454310 | 0.83 | CCR5 (0.55) | OPRM1CCR5 | |
| SCHEMBL3038736 | 0.82 | CCR5 (0.62) | OPRM1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180513-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-20 | — | — | EP | disclosed |