Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455496 | 0.85 | OPRM1 (0.58) | CCR5OPRM1CCR3SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL7465772 | 0.83 | CCR5 (0.70) | CCR5OPRM1 | |
| SCHEMBL7470084 | 0.81 | OPRM1 (0.53) | CCR5OPRM1ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7470211 | 0.80 | CCR5 (0.63) | CCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL7463538 | 0.80 | CCR5 (0.56) | CCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL7453187 | 0.80 | CCR5 (0.63) | CCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL7454310 | 0.80 | CCR5 (0.55) | CCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL7464027 | 0.79 | CCR5 (0.59) | CCR5OPRM1CCR3 | |
| SCHEMBL7465426 | 0.79 | SLC6A2 (0.49) | CCR5OPRM1 | |
| SCHEMBL3038736 | 0.79 | CCR5 (0.62) | CCR5OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180513-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-20 | — | — | EP | disclosed |