Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1864108 | 0.81 | KDM4E (0.58) | CYP19A1MAOBCA12CA1CA2 | |
| SCHEMBL1500219 | 0.81 | CYP3A4 (0.61) | AKR1B1CYP19A1MAOAMAOBCA12 | |
| SCHEMBL1865302 | 0.81 | KDM4E (0.66) | CYP19A1MAOBCA12CA1CA2 | |
| SCHEMBL5275063 | 0.76 | AKR1B1 (1.00) | AKR1B1CYP19A1MAOAMAOBCA12 | |
| SCHEMBL6545814 | 0.76 | FLT3 (0.54) | MAOAMAOBCA12CA1CA2 | |
| SCHEMBL5715426 | 0.75 | MAPT (0.52) | AKR1B1CYP19A1MAOAMAOBCA12 | |
| SCHEMBL6036796 | 0.74 | KDM4E (0.52) | CYP3A4HPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2318178 | 0.74 | TNKS (0.52) | MAOBCYP1A2CYP3A4ALDH1A1MEN1 | |
| SCHEMBL5220493 | 0.74 | GABRP (0.52) | CA12CA9CYP3A4SMN1; SMN2MAPK1 | |
| SCHEMBL5188789 | 0.72 | AKR1B1 (0.76) | AKR1B1CYP19A1MAOAMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739892-B1 | Chromone derivatives | NOVARTIS AG (CH) | 2002-09-25 | — | — | EP | disclosed |
| EP-0739892-A2 | Chromone derivatives | CIBA-GEIGY AG (CH) | 1996-10-30 | — | — | EP | disclosed |