Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1607138 | 0.85 | LMNA (0.75) | LMNAPGRESR1ESR2TSHR | |
| SCHEMBL3917903 | 0.84 | LMNA (0.60) | LMNAPGRESR1ESR2TSHR | |
| SCHEMBL3917902 | 0.84 | LMNA (0.60) | LMNAPGRESR1ESR2TSHR | |
| SCHEMBL3913946 | 0.83 | ESR1 (0.43) | LMNAESR1ESR2TSHRTDP1 | |
| SCHEMBL8746277 | 0.81 | TSHR (0.42) | LMNATSHRTDP1CYP2C9CYP3A4 | |
| SCHEMBL9754371 | 0.81 | S1PR2 (0.44) | LMNAESR1ESR2CHRM2SLC6A2 | |
| SCHEMBL6612632 | 0.80 | LMNA (0.56) | LMNAPGRESR1ESR2TSHR | |
| SCHEMBL547630 | 0.80 | LMNA (0.56) | LMNAPGRESR1ESR2CYP3A4 | |
| SCHEMBL9498329 | 0.80 | LMNA (0.56) | LMNAPGRESR1ESR2ADRB2 | |
| SCHEMBL5988792 | 0.80 | LMNA (0.56) | LMNAPGRESR1ESR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534547-B2 | Optically active compound and photosensitive resin composition | OSAKA GAS COMPANY LIMITED (JP) | 2009-05-19 | — | — | US | disclosed |
| EP-1030665-A4 | THERAPEUTIC USES OF QUINOLINE DERIVATIVES | AVENTIS PHARM PROD INC (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-1030665-A1 | THERAPEUTIC USES OF QUINOLINE DERIVATIVES | Aventis Pharmaceuticals Products Inc. (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999020275-A1 | THERAPEUTIC USES OF QUINOLINE DERIVATIVES | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-04-29 | — | — | WO | disclosed |
| US-4064086-A | SPIROLACTONES | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1977-12-20 | — | — | US | disclosed |