Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 10/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948405 | 0.82 | ALDH1A1 (0.67) | ALDH1A1MAPTNPSR1LMNAMEN1 | |
| SCHEMBL6948401 | 0.82 | ALDH1A1 (0.67) | ALDH1A1MAPTNPSR1LMNAMEN1 | |
| SCHEMBL6666397 | 0.80 | CA1 (0.47) | ALDH1A1MAPTNPSR1LMNAMEN1 | |
| SCHEMBL7464098 | 0.79 | PARP1 (0.44) | ALDH1A1MAPTNPSR1LMNAMEN1 | |
| SCHEMBL6664649 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPTNPSR1LMNAMEN1 | |
| SCHEMBL6664645 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPTNPSR1LMNAMEN1 | |
| SCHEMBL2578206 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPTNPSR1LMNAMEN1 | |
| SCHEMBL29275316 | 0.72 | MAPT (0.88) | ALDH1A1MAPTNPSR1LMNAMEN1 | |
| SCHEMBL7464335 | 0.70 | MAPT (0.38) | ALDH1A1MAPTNPSR1LMNAMEN1 | |
| SCHEMBL10736506 | 0.70 | MEN1 (0.47) | ALDH1A1MAPTNPSR1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235826-A1 | QUINUCLIDINE ACRYLAMIDES | AstraZeneca AB (SE) | 2002-09-04 | — | — | EP | claimed |
| WO-2001029034-A1 | QUINUCLIDINE ACRYLAMIDES | ASTRAZENECA AB (SE) | 2001-04-26 | — | — | WO | claimed |