Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15308500 | 0.72 | ALDH1A1 (0.45) | HTR6ALDH1A1HPGDHSD17B10PTGS2 | |
| SCHEMBL7453195 | 0.71 | SMPD3 (0.43) | JAK2HTR6HPGDPIK3CGPDE2A | |
| SCHEMBL7450810 | 0.70 | TSHR (0.46) | HTR6ALDH1A1HPGDHSD17B10PIK3CG | |
| SCHEMBL7456267 | 0.70 | KDM4E (0.48) | HTR6ALDH1A1HPGDHSD17B10PIK3CG | |
| SCHEMBL16630785 | 0.69 | ALDH1A1 (0.42) | HTR6ALDH1A1HPGDHSD17B10PTGS2 | |
| Hydrochloric Acid SCHEMBL8800842 | 0.69 | TSHR (0.45) | HTR6ALDH1A1HPGDHSD17B10PIK3CG | |
| SCHEMBL7465054 | 0.69 | MEN1 (0.42) | ALDH1A1HPGDHSD17B10PIK3CGLMNA | |
| SCHEMBL23047161 | 0.67 | PDE10A (0.44) | HTR6ALDH1A1HPGDHSD17B10PIK3CG | |
| SCHEMBL23023571 | 0.67 | ADORA2A (0.40) | JAK2HTR6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL21526649 | 0.67 | ALDH1A1 (0.41) | HTR6ALDH1A1HPGDHSD17B10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | L'OREAL SA (FR) | 2002-12-05 | — | — | US | claimed |
| EP-1175198-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2002-01-30 | — | — | EP | claimed |
| WO-2001062220-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2001-08-30 | — | — | WO | claimed |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | L'OREAL SA (FR) | 2002-12-05 | — | — | US | disclosed |
| EP-1175198-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2002-01-30 | — | — | EP | disclosed |
| WO-2001062220-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2001-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | FH, KRT18, CYB5R3 | JAK2 4772/4885HTR6 2136/4885MAT2A 1607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.