Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.39 |
| ▸ | F10 | P00742 | 7/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.39 |
| ▸ | F12 | P00748 | 6/20 | 0.39 |
| ▸ | F7 | P08709 | 6/20 | 0.39 |
| ▸ | F9 | P00740 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28915050 | 0.68 | ADRA1D (0.44) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7551592 | 0.66 | CYP2A6 (0.37) | — | |
| Trifluoroacetic Acid SCHEMBL6435993 | 0.66 | IDO1 (0.50) | — | |
| Trifluoroacetic Acid SCHEMBL3582556 | 0.64 | LOXL2 (0.42) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL3571368 | 0.64 | MEN1 (0.40) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL6077294 | 0.64 | F2 (0.35) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL29484053 | 0.61 | TAAR1 (0.64) | F2 | |
| Trifluoroacetic Acid SCHEMBL29484054 | 0.61 | TAAR1 (0.64) | F2 | |
| Trifluoroacetic Acid SCHEMBL34475873 | 0.61 | FFAR1 (0.43) | — | |
| SCHEMBL29876674 | 0.61 | CYP2A6 (0.46) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064559-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |