Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467486 | 0.85 | KMT2A (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7459166 | 0.81 | MAOA (0.41) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL7453978 | 0.80 | L3MBTL1 (0.41) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL7456534 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7462764 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL7468230 | 0.77 | MAOA (0.37) | ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7463350 | 0.76 | MAOA (0.44) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6606357 | 0.75 | MAOA (0.39) | RAB9A | |
| SCHEMBL7457919 | 0.75 | MAOA (0.44) | ALDH1A1KMT2ACYP2C9CYP2C19RAB9A | |
| SCHEMBL7462406 | 0.74 | MAOA (0.40) | CYP2C9CYP2C19RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498179-B1 | SUCH AS 4-(4-CHLOROPHENYL)-5-(3-(2-METHOXYPHENOXY)PROPYL)-2-(2-METHYL-1 -IMIDAZOLYL)OXAZOLE; INSULIN SECERTION PROMOTING AND BLOOD SUGAR DEPRESSING EFFECT; DIABETES; LOW TOXICITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-12-24 | — | — | US | disclosed |
| EP-0891340-B1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-11-13 | — | — | EP | disclosed |
| US-6177452-B1 | ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-23 | — | — | US | disclosed |