Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628683 | 0.84 | ALDH1A1 (0.50) | CRHBPCRHR2MAPTHPGDL3MBTL1 | |
| SCHEMBL27863288 | 0.77 | CRHBP (0.55) | CRHBPCRHR2MAPTHPGDL3MBTL1 | |
| SCHEMBL10458259 | 0.75 | CRHBP (0.45) | CRHBPCRHR2MAPTHPGDL3MBTL1 | |
| SCHEMBL6553212 | 0.73 | MAPT (0.60) | CRHBPCRHR2MAPTHPGDL3MBTL1 | |
| SCHEMBL293916 | 0.72 | MAPT (0.72) | CRHBPCRHR2MAPTHPGDL3MBTL1 | |
| SCHEMBL12443496 | 0.71 | CRHBP (0.57) | CRHBPCRHR2MAPTHPGDL3MBTL1 | |
| SCHEMBL31715811 | 0.70 | MAPT (0.73) | CRHBPCRHR2MAPTHPGDL3MBTL1 | |
| SCHEMBL14871770 | 0.70 | MAPK1 (0.61) | CRHBPCRHR2MAPTMEN1KMT2A | |
| SCHEMBL11023586 | 0.70 | MEN1 (0.50) | CRHBPCRHR2MAPTL3MBTL1MEN1 | |
| SCHEMBL3272499 | 0.70 | MAPT (0.73) | CRHBPCRHR2MAPTHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100809-A4 | RNA TARGETED 2'-MODIFIED OLIGONUCLEOTIDES THAT ARE CONFORMATIONALLY PREORGANIZED | ISIS PHARMACEUTICALS INC (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-1100809-A1 | RNA TARGETED 2'-MODIFIED OLIGONUCLEOTIDES THAT ARE CONFORMATIONALLY PREORGANIZED | ISIS PHARMACEUTICALS, INC. (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006590-A1 | RNA TARGETED 2'-MODIFIED OLIGONUCLEOTIDES THAT ARE CONFORMATIONALLY PREORGANIZED | ISIS PHARMACEUTICALS, INC. (US) | 2000-02-10 | — | — | WO | disclosed |