Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553212 | 0.78 | MAPT (0.60) | CRHBPCRHR2MAPTMEN1KMT2A | |
| SCHEMBL7457060 | 0.77 | CRHBP (0.50) | CRHBPCRHR2MAPTMEN1KMT2A | |
| SCHEMBL293916 | 0.76 | MAPT (0.72) | CRHBPCRHR2MAPTMEN1KMT2A | |
| SCHEMBL29868372 | 0.76 | MAPT (0.73) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL11748105 | 0.75 | MAPT (0.45) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL12443496 | 0.75 | CRHBP (0.57) | CRHBPCRHR2MAPTMEN1KMT2A | |
| SCHEMBL31715811 | 0.75 | MAPT (0.73) | CRHBPCRHR2MAPTMEN1KMT2A | |
| SCHEMBL3272499 | 0.74 | MAPT (0.73) | CRHBPCRHR2MAPTMEN1KMT2A | |
| SCHEMBL7813399 | 0.73 | MEN1 (0.72) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL265235 | 0.73 | CRHBP (0.55) | CRHBPCRHR2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101407476-B | M-bis(arene) polysubstituted aniline compound as non-nucleoside HIV reverse transcriptase inhibitor, and preparation and use thereof | INST PHARM & TOXICOLOGY AMMS | 2012-07-18 | — | — | CN | disclosed |