Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.53 |
| ▸ | PDE4A | P27815 | 3/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452667 | 0.88 | LMNA (0.48) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL27482337 | 0.84 | ADORA2B (0.70) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL7557802 | 0.84 | ADORA2B (0.57) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL7455573 | 0.83 | ADORA2B (0.56) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL7458605 | 0.83 | ADORA2B (0.58) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8656403 | 0.82 | ADORA2B (0.55) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8660068 | 0.81 | ADORA2B (0.54) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8660222 | 0.81 | ADORA2B (0.56) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL7465081 | 0.80 | ADORA2B (0.55) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8660141 | 0.78 | ADORA2B (0.53) | ADORA2BPDE4AADORA2APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771813-B1 | Alkylxanthine phosphonates and alkylxanthine phosphine oxydes and their use as medicines | HOECHST AG (DE) | 2002-01-16 | — | — | EP | disclosed |
| EP-0771813-A1 | Alkylxanthine phosphonates and alkylxanthine phosphine oxydes and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |