Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864209 | 0.91 | HPSE (0.62) | ALDH1A1NR1H4KMT2AFFAR1MEN1 | |
| SCHEMBL7373419 | 0.88 | ITGB3 (0.66) | ALDH1A1NR1H4KMT2AFFAR1MEN1 | |
| SCHEMBL7457481 | 0.84 | NR1H4 (0.67) | ALDH1A1NR1H4KMT2AFFAR1MEN1 | |
| SCHEMBL4099538 | 0.83 | KMT2A (0.57) | ALDH1A1NR1H4KMT2AFFAR1MEN1 | |
| SCHEMBL7453923 | 0.83 | ITGB3 (0.67) | ALDH1A1KMT2AMEN1ITGB3ITGA2B | |
| SCHEMBL7381598 | 0.83 | ITGB3 (0.67) | ALDH1A1KMT2AMEN1ITGB3ITGA2B | |
| SCHEMBL9303751 | 0.82 | ITGB3 (0.62) | KMT2AMEN1HPSEITGB3ITGA2B | |
| SCHEMBL7371397 | 0.82 | PPARA (0.53) | ALDH1A1KMT2AFFAR1MEN1TP53 | |
| Hydrochloric Acid SCHEMBL7319435 | 0.82 | KMT2A (0.56) | ALDH1A1NR1H4KMT2AFFAR1MEN1 | |
| SCHEMBL7856474 | 0.81 | SIRT2 (0.51) | ALDH1A1NR1H4KMT2AHPSEAGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-B1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-02-06 | — | — | EP | claimed |