Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.48 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864215 | 0.90 | HPSE (0.60) | NR1H4FFAR1MEN1KMT2ATP53 | |
| SCHEMBL7373424 | 0.89 | ITGB3 (0.64) | NR1H4FFAR1MEN1KMT2ATP53 | |
| SCHEMBL7381611 | 0.86 | ITGB3 (0.64) | NR1H4FFAR1MEN1KMT2ATP53 | |
| SCHEMBL7381617 | 0.86 | ITGB3 (0.64) | NR1H4FFAR1MEN1KMT2ATP53 | |
| SCHEMBL7378626 | 0.85 | ITGB3 (0.51) | NR1H4FFAR1MEN1KMT2ATP53 | |
| SCHEMBL7378200 | 0.84 | ITGB3 (0.56) | NR1H4ITGB3ITGA2BITGB1ITGAV | |
| SCHEMBL7378198 | 0.84 | ITGB3 (0.56) | NR1H4ITGB3ITGA2BITGB1ITGAV | |
| SCHEMBL7457847 | 0.84 | MEN1 (0.51) | NR1H4FFAR1MEN1KMT2ATP53 | |
| SCHEMBL7378809 | 0.84 | NR1H4 (0.50) | NR1H4FFAR1MEN1KMT2ATP53 | |
| SCHEMBL7457465 | 0.84 | ALDH1A1 (0.67) | NR1H4FFAR1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-B1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-02-06 | — | — | EP | claimed |