Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460203 | 0.93 | ITGB3 (0.43) | ITGB3ITGA2BF10CACNA1BADORA2A | |
| SCHEMBL8892492 | 0.88 | ITGB3 (0.49) | ITGB3ITGA2BF10ADORA2A | |
| SCHEMBL7468374 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BF10RBP4 | |
| SCHEMBL8892912 | 0.82 | ADORA2A (0.50) | ITGB3ITGA2BF10ADORA2A | |
| SCHEMBL7461228 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2BF10LY96CACNA1B | |
| SCHEMBL7460284 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2BF10RBP4 | |
| SCHEMBL7463619 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2BF10RBP4 | |
| SCHEMBL7239008 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2BF10 | |
| SCHEMBL31524118 | 0.78 | EPHX2 (0.48) | ITGB3ITGA2BPOLBMAPTTDP1 | |
| SCHEMBL8892462 | 0.77 | ITGB3 (0.49) | ITGB3ITGA2BF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697408-B1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 2002-01-23 | — | — | EP | disclosed |
| EP-0697408-A1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1996-02-21 | — | — | EP | disclosed |