Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | IL2 | P60568 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892492 | 0.90 | ITGB3 (0.49) | ADORA2AITGB3ITGA2BF10ITGB1 | |
| SCHEMBL7460203 | 0.90 | ITGB3 (0.43) | ADORA2AITGB3ITGA2BF10ALDH1A1 | |
| SCHEMBL8892462 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BF10ALDH1A1 | |
| SCHEMBL7457540 | 0.82 | ITGB3 (0.44) | ADORA2AITGB3ITGA2BF10 | |
| SCHEMBL8892944 | 0.81 | ITGB3 (0.49) | ITGB3ITGA2BF10ALDH1A1 | |
| SCHEMBL7462112 | 0.80 | ADORA2A (0.54) | ADORA2AITGB3ITGA2BF10ITGB1 | |
| SCHEMBL7460284 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2BF10ALDH1A1GRM2 | |
| SCHEMBL7237450 | 0.76 | ITGB3 (0.49) | ITGB3ITGA2BF10ALDH1A1GRM2 | |
| SCHEMBL7456647 | 0.76 | ITGB3 (0.49) | ITGB3ITGA2BF10ALDH1A1GRM2 | |
| SCHEMBL7468374 | 0.76 | ITGB3 (0.43) | ITGB3ITGA2BF10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |