Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.35 |
| ▸ | ADH5 | P11766 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892912 | 0.90 | ADORA2A (0.50) | ITGB3ITGA2BF10ADORA2AITGB1 | |
| SCHEMBL7457540 | 0.88 | ITGB3 (0.44) | ITGB3ITGA2BF10ADORA2A | |
| SCHEMBL8892462 | 0.87 | ITGB3 (0.49) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL8892944 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL7463401 | 0.79 | ITGB3 (0.45) | ITGB3ITGA2BF10ADORA2ANAALAD2 | |
| SCHEMBL8893341 | 0.78 | ITGB3 (0.56) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL7460284 | 0.77 | ITGB3 (0.46) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL7468374 | 0.75 | ITGB3 (0.43) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL8893573 | 0.73 | ADORA2A (0.48) | ADORA2ANAALAD2 | |
| SCHEMBL7456647 | 0.73 | ITGB3 (0.49) | ITGB3ITGA2BF10ADH5XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |