Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453153 | 0.91 | DPP8 (0.35) | DPP8DPP9HSD11B1SIGMAR1CCR2 | |
| SCHEMBL7453157 | 0.91 | DPP8 (0.35) | DPP8DPP9HSD11B1SIGMAR1CCR2 | |
| SCHEMBL8441215 | 0.88 | HSD11B1 (0.45) | DPP8DPP9HSD11B1SIGMAR1EPHX2 | |
| SCHEMBL28804784 | 0.88 | HSD11B1 (0.45) | DPP8DPP9HSD11B1SIGMAR1EPHX2 | |
| SCHEMBL22406792 | 0.88 | HSD11B1 (0.45) | DPP8DPP9HSD11B1SIGMAR1EPHX2 | |
| SCHEMBL8436718 | 0.88 | HSD11B1 (0.45) | DPP8DPP9HSD11B1SIGMAR1EPHX2 | |
| SCHEMBL28804781 | 0.88 | HSD11B1 (0.45) | DPP8DPP9HSD11B1SIGMAR1EPHX2 | |
| SCHEMBL8436720 | 0.88 | HSD11B1 (0.45) | DPP8DPP9HSD11B1SIGMAR1EPHX2 | |
| SCHEMBL7463311 | 0.86 | ALDH1A1 (0.38) | DPP8DPP9HSD11B1 | |
| SCHEMBL8095171 | 0.85 | REN (0.37) | DPP8DPP9HSD11B1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882728-B1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO CO (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |