Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.64 |
| ▸ | CDK2 | P24941 | 15/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 11/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 12/20 | 0.57 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.57 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.57 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.57 |
| ▸ | CDK1 | P06493 | 2/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.53 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192977 | 1.00 | FLT3 (0.64) | FLT3CDK2PDGFRACCNE1CCNE2 | |
| SCHEMBL5194072 | 0.92 | FLT3 (0.63) | FLT3CDK2PDGFRACCNE1CCNE2 | |
| SCHEMBL5194082 | 0.92 | FLT3 (0.63) | FLT3CDK2PDGFRACCNE1CCNE2 | |
| SCHEMBL5627025 | 0.90 | FLT3 (0.61) | FLT3CDK2PDGFRACCNE1CCNE2 | |
| SCHEMBL7460046 | 0.89 | CDK2 (0.70) | FLT3CDK2PDGFRACCNE1CCNE2 | |
| SCHEMBL5197008 | 0.89 | CDK2 (0.70) | FLT3CDK2PDGFRACCNE1CCNE2 | |
| Hydrochloric Acid SCHEMBL5628928 | 0.89 | CDK2 (0.69) | FLT3CDK2PDGFRACCNE1CCNE2 | |
| Hydrochloric Acid SCHEMBL27560215 | 0.89 | CDK2 (0.69) | FLT3CDK2PDGFRACCNE1CCNE2 | |
| SCHEMBL7458142 | 0.83 | FLT3 (0.62) | FLT3CDK2PDGFRACCNE1CCNE2 | |
| SCHEMBL5195263 | 0.83 | FLT3 (0.62) | FLT3CDK2PDGFRACCNE1CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183256-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071543-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2000-11-30 | — | — | WO | disclosed |