Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455377 | 0.95 | GAA (0.50) | GAAALDH1A1KDM4ENPC1CDK1 | |
| SCHEMBL9269903 | 0.93 | NPC1 (0.42) | GAAALDH1A1KDM4ENPC1TP53 | |
| SCHEMBL7454655 | 0.92 | GAA (0.45) | GAACDK1TP53GLAMAPT | |
| SCHEMBL7464037 | 0.92 | GAA (0.47) | GAAALDH1A1KDM4ENPC1CDK1 | |
| SCHEMBL7455217 | 0.86 | GAA (0.47) | GAAALDH1A1KDM4ENPC1CDK1 | |
| SCHEMBL7453942 | 0.86 | GAA (0.53) | GAAALDH1A1KDM4ENPC1CDK1 | |
| SCHEMBL9274753 | 0.85 | ALDH1A1 (0.42) | GAAALDH1A1KDM4ENPC1TP53 | |
| SCHEMBL7455302 | 0.84 | ALOX15 (0.41) | GAAALDH1A1KDM4ENPC1TP53 | |
| SCHEMBL9208572 | 0.84 | ALDH1A1 (0.43) | GAAALDH1A1KDM4ENPC1TP53 | |
| SCHEMBL9701450 | 0.83 | ALDH1A1 (0.40) | GAAALDH1A1KDM4ENPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639190-B1 | PYRIDINE SULFONYL UREA DERIVATIVES | LG CHEM INVESTMENT LTD (KR) | 2002-01-09 | — | — | EP | claimed |
| US-5461026-A | Pyridine sulfonyl urea derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-10-24 | — | — | US | claimed |
| EP-0639190-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-02-22 | — | — | EP | claimed |
| WO-1992014728-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-09-03 | — | — | WO | claimed |
| EP-0639190-B1 | PYRIDINE SULFONYL UREA DERIVATIVES | LG CHEM INVESTMENT LTD (KR) | 2002-01-09 | — | — | EP | disclosed |