Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212510 | 0.92 | ALDH1A1 (0.43) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL9701450 | 0.91 | ALDH1A1 (0.40) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL9216687 | 0.86 | ALDH1A1 (0.39) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL7455377 | 0.86 | GAA (0.50) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL7458934 | 0.85 | GAA (0.45) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL7454655 | 0.83 | GAA (0.45) | SMN1; SMN2MAPTTP53GAA | |
| SCHEMBL7455302 | 0.82 | ALOX15 (0.41) | ALDH1A1KDM4ENPC1SMN1; SMN2TP53 | |
| SCHEMBL9269903 | 0.81 | NPC1 (0.42) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL10999502 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL7464037 | 0.77 | GAA (0.47) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639190-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-02-22 | — | — | EP | claimed |
| WO-1992014728-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-09-03 | — | — | WO | claimed |