Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NPR3 | P17342 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990249 | 0.98 | IDH1 (0.31) | IDH1IDH2GAATDP1CYP2C9 | |
| SCHEMBL9742736 | 0.94 | IDH1 (0.32) | IDH1IDH2 | |
| SCHEMBL9428391 | 0.92 | KMT2A (0.41) | CYP2C9NPR3CYP2C19LMNAALDH1A1 | |
| SCHEMBL8651933 | 0.89 | — | — | |
| SCHEMBL9428503 | 0.88 | CYP2D6 (0.30) | — | |
| SCHEMBL20608531 | 0.87 | GAA (0.33) | IDH1IDH2GAATDP1 | |
| SCHEMBL607239 | 0.86 | — | — | |
| SCHEMBL714017 | 0.86 | GAA (0.36) | IDH1IDH2GAATDP1LMNA | |
| SCHEMBL692773 | 0.86 | ALDH1A1 (0.31) | IDH1IDH2ALDH1A1 | |
| SCHEMBL7479465 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889085-B1 | N,N',N'''-Tris(2,4-bis(1-hydrocarbyloxy-2,2,6,6,-tetramethylpiperidin-4-yl)alkylamino)-s-triazin-6-yl)-3,3'-ethylenediiminodipropylamines, their isomers and bridged derivatives and polymer compositions stabilized therewith | CIBA SC HOLDING AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| EP-0889085-A2 | N,N',N'''-Tris(2,4-bis(1-hydrocarbyloxy-2,2,6,6,-tetramethylpiperidin-4-yl)alkylamino)-s-triazin-6-yl)-3,3'-ethylenediiminodipropylamines, their isomers and bridged derivatives and polymer compositions stabilized therewith | Ciba SC Holding AG (CH) | 1999-01-07 | — | — | EP | disclosed |
| US-5300544-A | Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-5216156-A | Stabilizers having functional groups which chemically bond with polymer substrates | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |