Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.48 |
| ▸ | TUBB | P07437 | 4/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6344050 | 0.93 | LMNA (0.58) | L3MBTL1LMNAHTTSMN1; SMN2TDP1 | |
| SCHEMBL6496116 | 0.82 | CYP1A1 (0.52) | MAPTL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6340655 | 0.82 | TUBB4A (0.53) | L3MBTL1LMNAHTTSMN1; SMN2TDP1 | |
| SCHEMBL2236652 | 0.81 | CYP1A1 (0.54) | L3MBTL1LMNAHTTSMN1; SMN2TDP1 | |
| SCHEMBL6341347 | 0.78 | TUBB4A (0.54) | CYP3A4MAPTL3MBTL1LMNAHTT | |
| SCHEMBL2236467 | 0.77 | PTGS2 (0.59) | MAPTLMNAHTTCYP1A1 | |
| Antiarol SCHEMBL7467110 | 0.76 | CYP1A1 (0.46) | CYP3A4MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL8818892 | 0.76 | TDP1 (0.68) | MAPTL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6340685 | 0.75 | CA1 (0.52) | MAPTCYP1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL2237499 | 0.74 | CYP19A1 (0.51) | CYP3A4LMNATDP1CYP1A1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181269-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000073264-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2000-12-07 | — | — | WO | disclosed |