SCHEMBL7459162

SCHEMBL7459162

Cc1nonc1C(=NO)c1ccc(F)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 6/20 0.40
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
RXFP1 Q9HBX9 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
HPGD P15428 2/20 0.32
ALPL P05186 1/20 0.32
ALPI P09923 1/20 0.32
GAA P10253 1/20 0.32
ALPG P10696 1/20 0.32
TYMP P19971 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PAX8 Q06710 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7459160 1.00 PKM (0.40) PKMESR1ESR2RAB9ANPC1
SCHEMBL6588745 0.83 PKM (0.46) PKMRXFP1ALDH1A1HTTSMN1; SMN2
SCHEMBL6587272 0.83 PKM (0.46) PKMRXFP1ALDH1A1HTTSMN1; SMN2
SCHEMBL6587279 0.83 PKM (0.46) PKMRXFP1ALDH1A1HTTSMN1; SMN2
SCHEMBL7453025 0.75 GAA (0.40) PKMESR1ESR2RAB9ANPC1
SCHEMBL7453029 0.75 GAA (0.40) PKMESR1ESR2RAB9ANPC1
SCHEMBL7469592 0.75 GAA (0.40) PKMESR1ESR2RAB9ANPC1
SCHEMBL7464831 0.73 ESR1 (0.35) ESR1ESR2RAB9ANPC1ALDH1A1
SCHEMBL7464834 0.73 ESR1 (0.35) ESR1ESR2RAB9ANPC1ALDH1A1
SCHEMBL11523488 0.73 ESR1 (0.50) ESR1ESR2RAB9ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1184382-A1 OXIME DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PESTICIDES DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-03-06 EP disclosed